| # | Player | Team | GP | G | A | P | +/- |
|---|---|---|---|---|---|---|---|
| 1 | Connor McDavid | EDM | 82 | 48 | 90 | 138 | 17 |
| 2 | Nikita Kucherov | TBL | 76 | 44 | 86 | 130 | 43 |
| 3 | Nathan MacKinnon | COL | 80 | 53 | 74 | 127 | 57 |
| 4 | Evan Bouchard | EDM | 82 | 21 |
| 74 |
| 95 |
| 25 |
| 5 | Nick Suzuki | MTL | 82 | 29 | 72 | 101 | 37 |
| 6 | David Pastrnak | BOS | 77 | 29 | 71 | 100 | 4 |
| 7 | Macklin Celebrini | SJS | 82 | 45 | 70 | 115 | 8 |
| 8 | Quinn Hughes | VAN, MIN | 74 | 7 | 69 | 76 | -4 |
| 9 | Mark Scheifele | WPG | 82 | 36 | 67 | 103 | 0 |
| 10 | Lane Hutson | MTL | 82 | 12 | 66 | 78 | 36 |
| 11 | Jack Eichel | VGK | 74 | 27 | 63 | 90 | 23 |
| 12 | Clayton Keller | UTA | 82 | 26 | 62 | 88 | 21 |
| 13 | Martin Necas | COL | 78 | 38 | 62 | 100 | 47 |
| 14 | Leon Draisaitl | EDM | 65 | 35 | 62 | 97 | 13 |
| 15 | Cale Makar | COL | 75 | 20 | 59 | 79 | 32 |
| 16 | Zach Werenski | CBJ | 75 | 22 | 59 | 81 | 7 |
| 17 | Mitch Marner | VGK | 81 | 24 | 56 | 80 | 17 |
| 18 | Artemi Panarin | NYR, LAK | 78 | 28 | 56 | 84 | -7 |
| 19 | Mikko Rantanen | DAL | 64 | 22 | 55 | 77 | 0 |
| 20 | Rasmus Dahlin | BUF | 77 | 19 | 55 | 74 | 18 |
| 21 | Miro Heiskanen | DAL | 77 | 9 | 54 | 63 | 9 |
| 22 | Mathew Barzal | NYI | 81 | 19 | 53 | 72 | 10 |
| 23 | Sebastian Aho | CAR | 79 | 27 | 53 | 80 | 11 |
| 24 | Kyle Connor | WPG | 82 | 39 | 53 | 92 | -2 |
| 25 | Lucas Raymond | DET | 80 | 25 | 51 | 76 | 1 |
| 26 | Erik Karlsson | PIT | 75 | 15 | 51 | 66 | 8 |
| 27 | Jason Robertson | DAL | 82 | 45 | 51 | 96 | 22 |
| 28 | Jake Guentzel | TBL | 81 | 38 | 50 | 88 | 13 |
| 29 | Charlie McAvoy | BOS | 69 | 11 | 50 | 61 | 13 |
| 30 | Moritz Seider | DET | 82 | 10 | 50 | 60 | 15 |
| 31 | Jack Hughes | NJD | 61 | 27 | 50 | 77 | 0 |
| 32 | Tim Stützle | OTT | 80 | 34 | 49 | 83 | 7 |
| 33 | William Nylander | TOR | 65 | 30 | 49 | 79 | -14 |
| 34 | Ryan O'Reilly | NSH | 81 | 25 | 49 | 74 | 8 |
| 35 | Mikhail Sergachev | UTA | 78 | 10 | 49 | 59 | 2 |
| 36 | Jesper Bratt | NJD | 82 | 22 | 49 | 71 | -11 |
| 37 | Jackson LaCombe | ANA | 82 | 10 | 48 | 58 | -2 |
| 38 | Darren Raddysh | TBL | 73 | 22 | 48 | 70 | 21 |
| 39 | John Carlson | WSH, ANA | 71 | 14 | 46 | 60 | 9 |
| 40 | Connor Bedard | CHI | 69 | 30 | 45 | 75 | -18 |
| 41 | Mark Stone | VGK | 60 | 28 | 45 | 73 | 26 |
| 42 | Sidney Crosby | PIT | 68 | 29 | 45 | 74 | 0 |
| 43 | Nikolaj Ehlers | CAR | 82 | 26 | 45 | 71 | 8 |
| 44 | Alex DeBrincat | DET | 82 | 41 | 44 | 85 | 8 |
| 45 | Mika Zibanejad | NYR | 81 | 34 | 44 | 78 | -20 |
| 46 | Luke Evangelista | NSH | 81 | 12 | 44 | 56 | 1 |
| 47 | Adam Fox | NYR | 55 | 9 | 44 | 53 | 5 |
| 48 | Kirill Kaprizov | MIN | 78 | 45 | 44 | 89 | 10 |
| 49 | Ivan Demidov | MTL | 82 | 19 | 43 | 62 | 3 |
| 50 | Matthew Knies | TOR | 79 | 23 | 43 | 66 | -30 |