| # | Player | Team | GP | G | A | P | +/- |
|---|---|---|---|---|---|---|---|
| 1 | Brett Kulak | EDM, PIT, COL | 83 | 1 | 11 | 12 | -4 |
| 2 | Barclay Goodrow | SJS | 82 | 5 | 7 | 12 | -18 |
| 3 | Alex Ovechkin | WSH | 82 | 32 | 32 | 64 | -5 |
| 4 | Macklin Celebrini |
| 82 |
| 45 |
| 70 |
| 115 |
| 8 |
| 5 | Yakov Trenin | MIN | 82 | 6 | 17 | 23 | 13 |
| 6 | Beckett Sennecke | ANA | 82 | 23 | 37 | 60 | -12 |
| 7 | Braden Schneider | NYR | 82 | 2 | 16 | 18 | -5 |
| 8 | Cody Ceci | LAK | 82 | 1 | 8 | 9 | -10 |
| 9 | Jonas Siegenthaler | NJD | 82 | 0 | 16 | 16 | -9 |
| 10 | Steven Stamkos | NSH | 82 | 42 | 24 | 66 | -17 |
| 11 | Matt Savoie | EDM | 82 | 18 | 19 | 37 | 6 |
| 12 | Clayton Keller | UTA | 82 | 26 | 62 | 88 | 21 |
| 13 | Esa Lindell | DAL | 82 | 6 | 26 | 32 | 30 |
| 14 | Adam Fantilli | CBJ | 82 | 24 | 35 | 59 | -13 |
| 15 | Ben Chiarot | DET | 82 | 5 | 10 | 15 | -9 |
| 16 | Drew O'Connor | VAN | 82 | 17 | 12 | 29 | -12 |
| 17 | Brady Skjei | NSH | 82 | 3 | 23 | 26 | -7 |
| 18 | John Tavares | TOR | 82 | 31 | 40 | 71 | -28 |
| 19 | Jack Drury | COL | 82 | 10 | 17 | 27 | 15 |
| 20 | Nick Suzuki | MTL | 82 | 29 | 72 | 101 | 37 |
| 21 | Matthew Schaefer | NYI | 82 | 23 | 36 | 59 | 13 |
| 22 | Sean Kuraly | BOS | 82 | 6 | 16 | 22 | 0 |
| 23 | Brenden Dillon | NJD | 82 | 3 | 12 | 15 | -13 |
| 24 | Matty Beniers | SEA | 82 | 20 | 30 | 50 | -8 |
| 25 | Fraser Minten | BOS | 82 | 17 | 18 | 35 | 21 |
| 26 | Juraj Slafkovský | MTL | 82 | 30 | 43 | 73 | 9 |
| 27 | Bowen Byram | BUF | 82 | 11 | 31 | 42 | 15 |
| 28 | Alex Laferriere | LAK | 82 | 21 | 23 | 44 | 3 |
| 29 | Gabriel Vilardi | WPG | 82 | 30 | 39 | 69 | -12 |
| 30 | Alexis Lafrenière | NYR | 82 | 24 | 33 | 57 | -7 |
| 31 | Pavel Dorofeyev | VGK | 82 | 37 | 27 | 64 | -3 |
| 32 | Darnell Nurse | EDM | 82 | 7 | 17 | 24 | -12 |
| 33 | Will Cuylle | NYR | 82 | 20 | 18 | 38 | -12 |
| 34 | Joel Edmundson | LAK | 82 | 2 | 21 | 23 | 14 |
| 35 | Dylan DeMelo | WPG | 82 | 3 | 16 | 19 | 7 |
| 36 | Anthony Beauvillier | WSH | 82 | 15 | 13 | 28 | 7 |
| 37 | Alex DeBrincat | DET | 82 | 41 | 44 | 85 | 8 |
| 38 | Mark Scheifele | WPG | 82 | 36 | 67 | 103 | 0 |
| 39 | Emmitt Finnie | DET | 82 | 13 | 17 | 30 | -10 |
| 40 | Noah Cates | PHI | 82 | 18 | 29 | 47 | 26 |
| 41 | Claude Giroux | OTT | 82 | 14 | 35 | 49 | 20 |
| 42 | Jack Quinn | BUF | 82 | 20 | 31 | 51 | 4 |
| 43 | Marcus Pettersson | VAN | 82 | 3 | 15 | 18 | -19 |
| 44 | Evan Bouchard | EDM | 82 | 21 | 74 | 95 | 25 |
| 45 | Nick Schmaltz | UTA | 82 | 33 | 41 | 74 | 17 |
| 46 | Sam Malinski | COL | 82 | 8 | 32 | 40 | 43 |
| 47 | Dawson Mercer | NJD | 82 | 20 | 22 | 42 | -2 |
| 48 | Adam Pelech | NYI | 82 | 4 | 12 | 16 | 4 |
| 49 | Brian Dumoulin | LAK | 82 | 2 | 15 | 17 | -1 |
| 50 | Brent Burns | COL | 82 | 12 | 23 | 35 | 33 |